//Chemesis2.0 //units are microMolar and sec, unless indicated /* ######## volume assumed 1e-12 Liters corresponds to 10 um cubed ######### */ float Volume = 1e-12 float um=1e-6 float K_mGluR = 4*{Volume}*{um}*6e23 /*molecules*/ float K_G = 25.0 float K_PLC = 5.0 float K_PIP2 = 160 // Kinetics of G protein activation and degradation float D5f =15, D5b =7.2 float D6f =1.8 //Vmax2 = D6f Km2 = (D6f + D5B)/D5f, used with mmenz object float Vmax2 =1.8, Km2 =0.6 float D7f = 9 /* aG decay, from Biddlecomb and Ross */ //kinetics of G_alpha binding to PLC float G2f =100, G2b =100 //kinetics of IP3 production and degradation /* values from Mitchell et al., Smrcka et al., Rack et al. */ float Vmax1 =0.58, kfplc=0.83, kbplc=0.1